The Art of the Soluble: Creativity and Originality in Science

This collection of eight pieces by Sir Peter Medawar, who shared the Nobel Prize in 1960 for his work in graft rejection leading to advances in the toleration of transplants, is anchored by the last two essays, “Two Conceptions of Science” and “Hypothesis and Imagination.” The point of the title is made in a review of Arthur Koestler’s The Act of Creation, which Medawar finds disappointing.